| Major Public Employers | ||
| Govt. \ Educational | Product \ Service | No. of Employees |
| Ector County I.S.D. | Public Education | 3,317 |
| Medical Center Hospital | County Hospital | 1,598 |
| City of Odessa | City Government | 833 |
| Ector County | Government | 659 |
| Texas Tech University Health Sciences Center | Education/ Medical | 453 |
| The University of Texas Permian Basin | Education | 345 |
| Odessa College | Education | 343 |