| Major Public Employers | ||
| Govt. \ Educational | Product \ Service | No. of Employees |
| Ector County I.S.D. | Public Education | 3,336 |
| Medical Center Hospital | County Hospital | 1,687 |
| City of Odessa | City Government | 884 |
| Ector County | Government | 628 |
| Odessa College | Education | 413 |
| Texas Tech University Health Sciences Center | Education/ Medical | 404 |
| The University of Texas Permian Basin | Education | 351 |