Below is a list of major employers in and around Odessa. For additional information about the employers in Odessa please contact us directly at 877.363.3772 or by email at info@odessaecodev.com.
| Top 20 Private Employers | ||
| Private Industry Employers | Product\Service | No. of Employees |
| Saulsbury Companies | Electric & Construction | 1350 |
| Halliburton Services | Oil & Gas | 997 |
| Odessa Regional Medical Center | Medical | 900 |
| Walmart | Retail | 895 |
| Nurses Unlimited, Inc. | Medical | 584 |
| Weatherford CPS | Oil & Gas | 510 |
| Investment Corporation of America | Financial | 467 |
| Bobby Cox Companies, Inc. | Retail/ Restaurants | 389 |
| Holloman Construction | Oil Field Construction | 350 |
| Family Dollar | Distribution | 330 |
| Albertson's | Retail Grocery | 301 |
| HEB | Retail Grocery | 300 |
| Sewell Ford Motor Company | Automotive | 258 |
| Southwest Convenience Stores | Service | 236 |
| Lithia Motors | Automotive | 235 |
| NOV Tuboscope | Service | 222 |
| Flint Energy Construction Co. | Construction | 210 |
| Lowe's Market Place | Retail Grocery | 189 |
| Jones Bros. Dirt & Paving | Construction | 177 |
| Sam's Wholesale | Retail | 165 |
| Major Public Employers | ||
| Govt. \ Educational | Product \ Service | No. of Employees |
| Ector County I.S.D. | Public Education | 3,317 |
| Medical Center Hospital | County Hospital | 1,598 |
| City of Odessa | City Government | 833 |
| Ector County | Government | 659 |
| Texas Tech University Health Sciences Center | Education/ Medical | 453 |
| The University of Texas Permian Basin | Education | 345 |
| Odessa College | Education | 343 |