Below is a list of major employers in and around Odessa. For additional information about the employers in Odessa please contact us directly at 877.363.3772 or by email at info@odessaecodev.com.
| Top 20 Private Employers | ||
| Private Industry Employers | Product\Service | No. of Employees |
| WalMart | Retail | 923 |
| Saulsbury Companies | Electric & Construction | 868 |
| Odessa Regional Hospital | Medical | 752 |
| Nurses Unlimited, Inc. | Medical | 596 |
| Bobby Cox Companies, Inc. | Retail/ Restaurants | 534 |
| Haliburton Services | Oil & Gas | 511 |
| Investment Corp. of America | Financial | 450 |
| Telvisa, Inc. | Customer Service | 400 |
| Weatherford CPS | Oil & Gas | 390 |
| Family Dollar | Distribution Center | 379 |
| Albertson's | Retail Grocery | 295 |
| HEB | Retail Grocery | 287 |
| Lithia Motors | Automotive | 240 |
| Southwest Convenience Stores | Service | 220 |
| Sewell Ford Motor Company | Automotive | 208 |
| Jones Bros. Dirt & Paving | Construction | 200 |
| Lowe's Market Place | Retail Grocery | 197 |
| NOV Tuboscope | Service | 185 |
| Sam's Wholesale | Retail | 161 |
| Sun Electric | Electric Contractor | 160 |
| Major Public Employers | ||
| Govt. \ Educational | Product \ Service | No. of Employees |
| Ector County I.S.D. | Public Education | 3,539 |
| Medical Center Hospital | County Hospital | 1,699 |
| City of Odessa | City Government | 905 |
| Ector County | Government | 637 |
| Odessa College | Education | 606 |
| Texas Tech University Health | Education/ Medical | 430 |
| University of Texas of the Permian Basin | Education | 351 |